Journal: PLoS Neglected Tropical Diseases

Article Title: The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical research

doi: 10.1371/journal.pntd.0007787

Figure Lengend Snippet: Instrument selection.

Article Snippet: Although the primary diagnostic platform for JMEDICC is the rapid and simple BioFire FilmArray Warrior Panel, which has been cleared for filovirus diagnostics by the US FDA, the team is also being trained on PCR to enable quantitative viral load analysis.

Techniques: Selection, Coagulation, Sample Prep, Virus, Polymerase Chain Reaction, Diagnostic Assay, Infection, High Throughput Screening Assay, RNA Extraction

Journal: The Journal of Hospital Infection

Article Title: Transmission dynamics and associated mortality of nosocomial COVID-19 throughout 2021: a retrospective study at a large teaching hospital in London

doi: 10.1016/j.jhin.2022.12.014

Figure Lengend Snippet: Epidemic curve demonstrating suspected cases of nosocomial SARS-CoV-2 infection throughout 2021, St George’s Hospital (SGH), London. COSHA, community-onset suspected healthcare-associated; HOHA, hospital-onset hospital acquired; HOIA, hospital-onset intermediate healthcare-associated; HOPA, hospital-onset probable hospital associated. (a) SARS-CoV-2 positive contacts visualized by both time of positive PCR and case attribution. (b) Weekly admitted patients to St. George’s Hospital, London with a positive SARS-CoV-2 PCR result throughout the study period (orange line) and weekly healthcare worker (HCW) absence rates presented as days of absence per 100 HCWs per week (blue line).

Article Snippet: In addition, any staff reporting symptoms underwent assessment by rapid (90-min turnaround) PCR (BioFire FilmArray or Xpert® Xpress CoV-2).

Techniques: Infection

Journal: The Journal of Hospital Infection

Article Title: Transmission dynamics and associated mortality of nosocomial COVID-19 throughout 2021: a retrospective study at a large teaching hospital in London

doi: 10.1016/j.jhin.2022.12.014

Figure Lengend Snippet: Raincloud plot showing the distribution of time to SARS-CoV-2 PCR positivity of susceptible contacts from the last point of contact to a SARS-CoV-2 index case. (Negative numbers indicate that the contact was diagnosed with COVID-19 whilst they were still exposed to the index case.) Given the recognized incubation period of SARS-CoV-2, it is unlikely that those cases detected after 14 days from time of exposure are directly linked to that index case. Those cases beyond this period are likely to represent a further unknown exposure event when the patient has come into contact with a symptomatic/asymptomatic SARS-CoV-2 individual later in the course of their hospital stay. In real-terms several areas of risk exist beyond the patient bay area, including interactions with visiting healthcare workers or moving around the hospital for diagnostic or treatment-based procedures, reflecting the difficulty of managing potential nosocomial cases.

Article Snippet: In addition, any staff reporting symptoms underwent assessment by rapid (90-min turnaround) PCR (BioFire FilmArray or Xpert® Xpress CoV-2).

Techniques: Incubation, Diagnostic Assay